VP4 relationships between porcine and other rotavirus serotypes

descriptionPublicationkeyboard_double_arrow_right Article 01 Mar 1991 English Publisher:Springer Science and Business Media LLCJournal:Archives of Virology, volume 116, pages 107-118 (issn: 0304-8608, eissn: 1432-8798,

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Authors: H S, Nagesha; I H, Holmes;

doi: 10.1007/bf01319235

pmid: 1705788

VP4 relationships between porcine and other rotavirus serotypes

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Abstract

VP4 relationship of Australian porcine rotaviruses were identified using genetic reassortants and MAbs. All porcine virus isolates except BEN-144 appeared to share VP4 antigenicity with OSU virus. VP4 and BEN-144 virus (Gottfried-like virus) showed some antigenic relationships with the human neonatal viruses ST-3 and RV-3. In addition, VP4 of porcine CRW-8 showed antigenic relationships with simian SA-11. RRV and also canine K9 viruses, while that of porcine TFR-41 showed at least one way VP4 antigenic relatedness with UK bovine rotavirus. Furthermore, BMI-1 virus which is antigenically similar to an American virus SB1-A (a naturally occurring reassortant) may have arisen similarly by gene reassortment in nature in Australia.

Related Organizations

University of Melbourne
Australia

Keywords

Rotavirus, Genes, Viral, Antibodies, Monoclonal, Antibodies, Viral, Epitopes, Capsid, Antibody Specificity, Animals, Capsid Proteins, Electrophoresis, Polyacrylamide Gel, Serotyping, Antigens, Viral

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