Polyethylene glycol-mediated infection with avian sarcoma viruses

descriptionPublicationkeyboard_double_arrow_right Article 01 Mar 1978 English Publisher:Springer Science and Business Media LLCJournal:Archives of Virology, volume 58, pages 55-59 (issn: 0304-8608, eissn: 1432-8798,

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Authors: W, Rohde; G, Pauli; J, Henning; R R, Friis;

doi: 10.1007/bf01315535

pmid: 211991

Polyethylene glycol-mediated infection with avian sarcoma viruses

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Abstract

In this communication we report that fusion of viral and cellular membranes by polyethylene glycol is a convenient approach to overcoming genetically determined resistance to infection. Using this method, avian sarcoma virus-transformed mammalian cells have been produced which serve as useful model systems for the study of Rous sarcoma virus-specific tumor antigens.

Related Organizations

Justus Liebig University Giessen
Germany

Keywords

Defective Viruses, Cell Transformation, Viral, Virus Replication, Cell Line, Polyethylene Glycols, Mice, Cell Transformation, Neoplastic, Avian Sarcoma Viruses, Antigens, Neoplasm, Transplantation Immunology, Animals, Antigens, Viral, Neoplasm Transplantation

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