Characterization of the equine influenza virus H 3 with monoclonal antibodies

descriptionPublicationkeyboard_double_arrow_right Article 01 Sep 1987 English Publisher:Springer Science and Business Media LLCJournal:Archives of Virology, volume 94, pages 339-346 (issn: 0304-8608, eissn: 1432-8798,

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Authors: J A, Appleton; D F, Antczak; A D, Lopes;

doi: 10.1007/bf01310728

pmid: 2437891

Characterization of the equine influenza virus H 3 with monoclonal antibodies

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Abstract

Mouse monoclonal antibodies specific for the hemagglutinin of the prototype equine-2 virus, A/equine/Miami/1/63 (H3, N8) demonstrated two related antigenic sites on the H3. One of the sites was detected on 14 H3 viruses isolated over a 22 year period (1963-1985). Variant viruses were selected with these antibodies at frequencies similar to those described for H3 hemagglutinins from human isolates.

Related Organizations

Cornell University
United States
College of New Jersey
United States

Keywords

Epitopes, Influenza A virus, Antibodies, Monoclonal, Hemagglutinins, Viral, Enzyme-Linked Immunosorbent Assay, Hemagglutination Inhibition Tests

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