Characterization of field isolates of suid herpesvirus 1 (Aujeszky's disease virus) as derivatives of attenuated vaccine strains

descriptionPublicationkeyboard_double_arrow_right Article 01 Sep 1992 English Publisher:Springer Science and Business Media LLCJournal:Archives of Virology, volume 124, pages 225-234 (issn: 0304-8608, eissn: 1432-8798,

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Authors: L S, Christensen; I, Medveczky; B S, Strandbygaard; Z, Pejsak;

doi: 10.1007/bf01309804

pmid: 1351387

Characterization of field isolates of suid herpesvirus 1 (Aujeszky's disease virus) as derivatives of attenuated vaccine strains

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Abstract

Field isolates of suid herpesvirus 1 (Aujeszky's disease virus) from Poland and Hungary were identified by restriction fragment pattern analysis as derivatives of attenuated vaccine strains. The Polish isolates were found to be related to the BUK-TK-900 strain (Suivac A) which is widely used as a live vaccine in Poland, and the Hungarian isolates were related to the Bartha K-61 vaccine strain widely used in Hungary. Pigs experimentally infected with derivatives of BUK-TK-900 or BUK-TK-900 itself were found to develop gI-antibodies, while pigs infected with derivatives of Bartha K-61 showed a gI-negative response.

Related Organizations

University of Copenhagen
Denmark
University of Veterinary Science
Myanmar
National Veterinary Research Institute
Poland

Keywords

Hungary, Pseudorabies, Swine, Foxes, Viral Vaccines, Vaccines, Attenuated, Herpesvirus 1, Suid, Blotting, Southern, Animals, Poland, Cells, Cultured, Polymorphism, Restriction Fragment Length

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