Characteristics of a cetacean morbillivirus isolated from a porpoise (Phocoena phocoena)

descriptionPublicationkeyboard_double_arrow_right Article 01 Mar 1992 United Kingdom English Publisher:Springer Science and Business Media LLCJournal:Archives of Virology, volume 125, pages 305-311 (issn: 0304-8608, eissn: 1432-8798,

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Authors: Welsh, M J; Lyons, C; Trudgett, A; Rima, B K; McCullough, S J; Orvell, C;

doi: 10.1007/bf01309647

pmid: 1642556

Characteristics of a cetacean morbillivirus isolated from a porpoise (Phocoena phocoena)

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Abstract

A virus isolated from a porpoise during the 1988 seal epizootic was shown to be a morbillivirus. In order to determine the relationship of the virus to phocine distemper virus (PDV) a battery of monoclonal antibodies raised against canine distemper virus (CDV), PDV or the porpoise isolate were assessed for their ability to bind to CDV, PDV or porpoise virus epitopes in indirect immunofluorescence assays and ELISAs. The porpoise isolate contained several unique epitopes and several epitopes present on CDV and PDV were absent on the porpoise isolate. The data presented in this study indicate that the porpoise virus is an antigenically distinct morbillivirus and as such has been tentatively named as delphinoid distemper virus (DDV).

Country

United Kingdom

Related Organizations

Queen's University Belfast
United Kingdom

Keywords

570, Mice, Inbred BALB C, Hybridomas, Distemper Virus, Dolphins, Antibodies, Monoclonal, Fluorescent Antibody Technique, Enzyme-Linked Immunosorbent Assay, Antibodies, Canine, Mice, Viral Proteins, Monoclonal, Paramyxoviridae, Animals, Viral, Antigens, Antigens, Viral, Distemper Virus, Canine, Vero Cells, Inbred BALB C

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