Smoking, the oral contraceptive pill, and Crohn's disease

descriptionPublicationkeyboard_double_arrow_right Article 01 Aug 1991 English Publisher:Springer Science and Business Media LLCJournal:Digestive Diseases and Sciences, volume 36, pages 1,147-1,150 (issn: 0163-2116, eissn: 1573-2568,

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Authors: A J, Wakefield; A M, Sawyerr; M, Hudson; A P, Dhillon; R E, Pounder;

doi: 10.1007/bf01297463

pmid: 1864207

Smoking, the oral contraceptive pill, and Crohn's disease

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Abstract

Both cigarette smoking and the oral contraceptive pill have been implicated as aggravating factors in Crohn's disease. Based upon the recent demonstration of multifocal gastrointestinal infarction in Crohn's disease, a possible pathogenic mechanism for this condition, we propose how smoking and the oral contraceptive pill may potentiate a tendency for focal thrombosis and hence exacerbate the activity of Crohn's disease.

Related Organizations

The Royal Free Hospital
United Kingdom
Royal Free London NHS Foundation Trust
United Kingdom

Keywords

Crohn Disease, Risk Factors, Smoking, Humans, Female, Thrombosis, Blood Coagulation, Contraceptives, Oral

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