Ammonium chloride and viral penetration

descriptionPublicationkeyboard_double_arrow_right Article 01 Dec 1967 English Publisher:Springer Science and Business Media LLCJournal:Archiv f�r die gesamte Virusforschung, volume 20, pages 411-420 (issn: 0304-8608, eissn: 1432-8798,

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Authors: M D, Eaton; A R, Scala;

doi: 10.1007/bf01275221

pmid: 5598022

Ammonium chloride and viral penetration

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Abstract

Quantitation of the effect of NH4Cl on viral penetration was done under conditions of single-cycle replication in a system using Krebs-2 ascites cells and influenza virus, which produces only unassembled viral structural protein. Penetration was measured by neutralization of adsorbed virus in the presence or absence of NH4Cl and comparison of yields of hemagglutinins after a 24 hour growth period.

Related Organizations

Harvard University
United States

Keywords

Culture Techniques, Immune Sera, Hemagglutinins, Viral, Orthomyxoviridae, Virus Replication, Antiviral Agents, Ammonium Chloride

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