The inhibition of variola minor virus multiplication by rifampicin

descriptionPublicationkeyboard_double_arrow_right Article 01 Sep 1970 English Publisher:Springer Science and Business Media LLCJournal:Archiv f�r die gesamte Virusforschung, volume 31, pages 281-292 (issn: 0304-8608, eissn: 1432-8798,

Copyright policy )

Authors: T H, Pennington;

doi: 10.1007/bf01253763

pmid: 4321450

The inhibition of variola minor virus multiplication by rifampicin

- Summary
- Subjects
- Metrics

Abstract

Rifampicin at concentrations of 100 μg/ml inhibits the growth of variola minor virus in HeLa cells. Synthesis of viral RNA, DNA, and early and late antigens occur in the presence of inhibitory concentrations of the drug, and its precise mode of action remains unclear.

Related Organizations

Medical Research Council
United Kingdom

Keywords

Immunodiffusion, Virus Cultivation, Immune Sera, Variola virus, Kidney, Virus Replication, Cell Line, Cricetinae, DNA, Viral, Animals, Autoradiography, RNA, Viral, Rabbits, Antigens, Rifampin, Uridine, HeLa Cells, Thymidine

Impact byBIP!

	selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	4
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Average
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Average