Parana, a new tacaribe complex virus from Paraguay

descriptionPublicationkeyboard_double_arrow_right Article 01 Dec 1970 English Publisher:Springer Science and Business Media LLCJournal:Archiv f�r die gesamte Virusforschung, volume 32, pages 379-388 (issn: 0304-8608, eissn: 1432-8798,

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Authors: P A, Webb; K M, Johnson; J B, Hibbs; M L, Kuns;

doi: 10.1007/bf01250066

pmid: 4993581

Parana, a new tacaribe complex virus from Paraguay

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Abstract

Parana virus, an agent isolated fromOryzomys buccinatus rodents trapped in the Misiones Department of Paraguay, was found to be related to the Tacaribe complex of viruses by complement-fixation tests, but was distinct by neutralization and direct immunofluorescent tests. It shares the basic properties of chloroform sensitivity, a ribonucleic acid core, and similar morphologic appearance with other viruses in the complex. No evidence for human infection was found in a limited survey. Neutralizing antibody was not demonstrable in 111 rodent sera, three of which were the animals from which the virus was isolated.

Related Organizations

United States Public Health Service
United States
National Institutes of Health
United States
National Institute of Allergy and Infectious Diseases
United States
National Institute of Health
Pakistan

Keywords

Immunodiffusion, Immune Sera, Complement Fixation Tests, Cesium, Fluorescent Antibody Technique, Haplorhini, Microbial Sensitivity Tests, Kidney, Cell Line, Mice, Chlorides, Paraguay, Cricetinae, Centrifugation, Density Gradient, Animals, Humans, RNA, Viral, Chloroform, Antigens, Arboviruses

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