Immunofluorescent assay of herpesvirus type 1 and type 2 antibodies in rabbit and human sera

descriptionPublicationkeyboard_double_arrow_right Article 01 Dec 1971 English Publisher:Springer Science and Business Media LLCJournal:Archiv f�r die gesamte Virusforschung, volume 35, pages 349-355 (issn: 0304-8608, eissn: 1432-8798,

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Authors: Pauli Leinikki;

doi: 10.1007/bf01241915

Immunofluorescent assay of herpesvirus type 1 and type 2 antibodies in rabbit and human sera

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Abstract

The immunofluorescent antibody technique was used to assay type-specific herpes simplex virus antibodies. Antibody responses were studied in three groups of patients: children with primary herpetic infections, neonates with generalized type 2 infection and adults with genital herpes infections. The results were compared with antibody responses seen in rabbits after experimental type 1 and 2 infections. In both rabbits and children with primary herpetic infections there was considerable cross-reaction, while in patients with genital herpes infections and in neonates there was very little cross-reaction.

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University of Helsinki
Finland

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