D1S80 allele frequencies in a Chinese population

descriptionPublicationkeyboard_double_arrow_right Article 01 May 1994 English Publisher:Springer Science and Business Media LLCJournal:International Journal of Legal Medicine, volume 107, pages 118-120 (issn: 0937-9827, eissn: 1437-1596,

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Authors: N E, Huang; R, Chakraborty; B, Budowle;

doi: 10.1007/bf01225597

pmid: 7893607

D1S80 allele frequencies in a Chinese population

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Abstract

Allele frequencies for the VNTR locus D1S80 were determined in a Chinese population sample using the polymerase chain reaction and subsequent analysis of the amplified products by polyacrylamide gel electrophoresis and silver staining. A total of 18 nominal D1S80 alleles were observed in 105 unrelated Chinese. The data demonstrate that D1S80 is highly polymorphic in Chinese with a heterozygosity of 90.5%. The D1S80 frequency distribution meets Hardy-Weinberg expectations. This D1S80 data can be used in forensic analyses and paternity tests to estimate the frequency of a DNA profile in a Chinese population.

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Keywords

Genotype, Chromosome Mapping, DNA, Minisatellite Repeats, Forensic Medicine, In Vitro Techniques, Polymerase Chain Reaction, Asian People, Gene Frequency, Humans, Electrophoresis, Polyacrylamide Gel, Alleles

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