The Cognitive Bias Questionnaire, the Present State Examination, the Beck Depression Inventory, and an expectancy of success measure were administered to depressed and nondepressed psychiatric inpatients. The depressed subjects selected significantly more depressed distortions on the Cognitive Bias Questionnaire than did the nondepressed subjects. Results also revealed that depressed distortion scores from the Cognitive Bias Questionnaire correlated significantly with measures of cognitive distortion obtained from the Beck Depression Inventory, the Present State Examination, and an experimental task. Although primary and secondary depressed groups did not differ significantly in their responses to the Cognitive Bias Questionnaire, depressed subjects who endorsed high levels of depressed distortion revealed significantly more cognitive symptoms of depression on the Beck Depression Inventory and the Present State Examination, and evidenced a nonsignificant trend to expect less success prior to an experimental task. Implications of these results for future research in this area are discussed.