It has been shown that oil of the best quality is obtained on its selective extraction by hexane. Subsequent extraction from the meal of gossypol by 70–80% aqueous, and then dry, acetone permits meal to be obtained with a light cream color containing 0.02% of free gossypol. The omission of dry acetone leads to a darkening of the meal. It has been established that it is possible to achieve a reduction in the consumption of solvents on the direct extraction of cottonseed flake by using weak oil and gossypol miscellas.