Allopurinol-induced granulomatous hepatitis

descriptionPublicationkeyboard_double_arrow_right Article 01 Sep 1976 English Publisher:Springer Science and Business Media LLCJournal:The American Journal of Digestive Diseases, volume 21, pages 804-806 (issn: 0002-9211, eissn: 1573-2568,

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Authors: C R, Espiritu; J, Alalu; L G, Glueckauf; J, Lubin;

doi: 10.1007/bf01073035

pmid: 961676

Allopurinol-induced granulomatous hepatitis

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Abstract

A 55-year-old female developed myalgias, arthralgias, fever, and abnormal liver function four weeks following intake of allopurinol. Granulomas were found in the liver. Withdrawal of allopurinol resulted in gradual improvement of clinical, biochemical, and histological lesions in this patient. To our knowledge, this is the second case report of granulomatous hepatitis following intake of allopurinol.

Related Organizations

University System of Ohio
United States
Miami University
United States
Mount Sinai Hospital
United States

Keywords

Granuloma, Liver, Allopurinol, Biopsy, Humans, Female, Chemical and Drug Induced Liver Injury, Middle Aged, Uric Acid

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