
doi: 10.1007/bf00917963
pmid: 1428545
Pattern reversals with a ramp-like temporal course evoke transient pattern electroretinograms (PERG) that are delayed and attenuated in comparison with responses evoked by a step-like course (abrupt pattern reversals). This delay depends on the reversal time and probably represents a measure for temporal characteristics of the activated retinal structures. A pattern reversal stimulator with adjustable reversal periods (matrix of 8 x 14 rectangular red light emitting diodes, element size 2 degrees x 1 degree, stimulus area 16 degrees x 14 degrees) was used to record transient PERGs from 20 glaucomatous eyes with early or moderate visual field damages (measured with computer perimetry). The q-wave (P1) amplitude difference between the glaucoma group and normal subjects with step-like reversal stimulation was not significant (P = 0.23). On the other hand, a highly significant separation (P < 0.0001) between both groups was possible using the P1 latency at ramp-like stimulation or the response latency shift between step and ramp-like stimulation (Pattern reversal time, 30 ms).
Time Factors, Vision Disorders, Middle Aged, Contrast Sensitivity, Pattern Recognition, Visual, Chronic Disease, Electroretinography, Humans, Visual Fields, Glaucoma, Open-Angle
Time Factors, Vision Disorders, Middle Aged, Contrast Sensitivity, Pattern Recognition, Visual, Chronic Disease, Electroretinography, Humans, Visual Fields, Glaucoma, Open-Angle
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