Suppression of human lymphocyte migration by PGE2

Name: Suppression of human lymphocyte migration by PGE2
Creator: D E, Van Epps
Keywords: 0301 basic medicine, Prostaglandins A, 0303 health sciences, 03 medical and health sciences, Cell Movement, Prostaglandins E, Prostaglandins F, Caseins, Complement C5, Humans

D E, Van Epps

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Inflammationarrow_drop_down

Inflammation

Article . 1981 . Peer-reviewed

License: Springer TDM

Data sources: Crossref

Inflammation

Article . 1981

Data sources: Europe PubMed Central

https://dx.doi.org/10.1007/bf0...

Article

Data sources: Microsoft Academic Graph

Suppression of human lymphocyte migration by PGE2

descriptionPublicationkeyboard_double_arrow_right Article 01 Mar 1981 English Publisher:Springer Science and Business Media LLCJournal:Inflammation, volume 5, pages 81-87 (issn: 0360-3997, eissn: 1573-2576,

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Authors: D E, Van Epps;

doi: 10.1007/bf00910782

pmid: 7228354

Suppression of human lymphocyte migration by PGE2

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Abstract

Prostaglandin (PG) E2 markedly inhibits casein- and C5a-stimulated lymphocyte migration in a concentration-dependent manner. Inhibition is observed with as low as 10(-9) M PGE2 and requires that PGE2 be present during cell locomotion. Studies with PGE1, PGF1 alpha, PGF2 alpha and PGA1 indicate that only PGE1 and PGE2 inhibit lymphocyte migration. These studies indicate that PGE2 may play a role in the regulation of the immune response at the level of lymphocyte locomotion.

Related Organizations

University of New Mexico
United States

Keywords

Prostaglandins A, Cell Movement, Prostaglandins E, Prostaglandins F, Caseins, Complement C5, Humans, Lymphocytes

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