The spatio-temporal variation of seismicity in the southern Peru and northern Chile seismic gaps is analyzed with teleseismic data (m b ≥ 5.5) between 1965 and 1991, to investigate whether these gaps present the precursory combination of compressional outer-rise and tensional downdip events observed in other subduction zones. In the outer-rise and the inner-trench (0 to 100 km distance from the trench) region, lower magnitude (5.0 ≤ m b < 5.5) events were also studied. The results obtained show that the gaps in southern Peru and northern Chile do not present compressional outer-rise events. However, both gaps show a continuous, tensional downdip seismicity. For both regions, the change from compressional to tensional regime along the slab occurs at a distance of about 160 km from the trench, apparently associated with the coupled-uncoupled transition of the interplate contact zone. In southern Peru, an increase of compressional seismicity near the interplate zone and of tensional events (5.0 ≤ m b ≤ 6.3) in the outer-rise and inner-trench regions is observed between 1987 and 1991. A similar distribution of seismicity in the outer-rise and inner-trench regions is observed with earthquakes (m b < 5.5). In northern Chile there is a relative absence of compressional activity (m b ≥ 5.5) near the interplate contact since the sequence of December 21, 1967. After that, only a cluster of low-magnitude compressional events has been located in the area 50 to 100 km from the trench. The compressional activity occurring near the interplate zone in both seismic gaps represents that a seismic preslip is occurring in and near the plate contact. Therefore, if this seismic preslip is associated with the maturity of the gap, the fact that it is larger in southern Peru than in northern Chile may reflect that the former gap is more mature than the latter. However, the more intense downdip tensional activity and the absence of compressional seismicity near the contact zone observed in northern Chile, may also be interpreted as evidence that northern Chile is seismically more mature than southern Peru. Therefore, the observed differences in the distribution of stresses and seismicity analyzed under simple models of stress accumulation and transfer in coupled subduction zones are not sufficient to assess the degree of maturity of a seismic gap.