
doi: 10.1007/bf00799338
pmid: 856349
Experiments were conducted on the myenteral plexus of the isolated stips of the small and large intestine; the presence of adrenosensitive cells which reacted to the application of different adrenaline (A) and noradrenaline (NA) concentrations by a distinct acceleration of the activity rhythm was demonstrated. NA with a greater range of action than A (from 10(-9) to 10(-5 g/ml) has the most marked effect. Introduction into the irrigating solution of phentholamine eliminated the mentioned effects in the majority of cases. "Silent" neurons without any spontaneous activity responded to the A and NA administration along with those possessing this activiy. As supposed, catecholamines could take a direct part in the modulation of the processes realized by the ganglionic neurons of the myenteral plexus.
Dose-Response Relationship, Drug, Epinephrine, Myenteric Plexus, Propranolol, Electrophysiology, Norepinephrine, Intestine, Small, Cats, Animals, Drug Interactions, Intestine, Large, Phentolamine
Dose-Response Relationship, Drug, Epinephrine, Myenteric Plexus, Propranolol, Electrophysiology, Norepinephrine, Intestine, Small, Cats, Animals, Drug Interactions, Intestine, Large, Phentolamine
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