A hydrogeological and geochemical study is presented for the San Severino Lucano region of southern Italy. In this region, groundwater circulation occurs in rocks lithologically different from one another (metaophiolites, carbonate rocks, etc.). Many springs drain this region. The Frido springs are the most important both for their great volume of flow and for their water quality. A water balance estimated for the recharge area of the Frido springs suggests that during the period 1938–1958 the evapotranspiration represents 54.8 percent, runoff 21.2 percent, and infiltration to groundwater 34 percent of rainfall. The springs studied have a meteoric origin and their waters are mostly acid carbonate-alkaline earth type. The reservoir rocks appear to be the only discriminating factors for the chemical composition of the waters analysed.