Regulation of endocytosis by the small GTP-ase Rab5
Copyright policy )Regulation of endocytosis by the small GTP-ase Rab5
Rab5 is a small GTPase associated with the plasma membrane and the early endosomes. Expression of wild type rab5 and a mutant protein defective in GTP-binding in BHK cells led to alterations in the rate of endocytosis and in the morphology of endocytic organelles. The results obtained suggest that rab5 is a rate limiting GTPase that regulate the kinetics of both lateral fusion of early endosomes and fusion of plasma membrane-derived endocytic vesicles with early endosomes.
GTP-Binding Proteins, Cricetinae, Mutation, Animals, Membrane Fusion, Endocytosis, Biotechnology, Cell Line, GTP Phosphohydrolases, rab5 GTP-Binding Proteins
GTP-Binding Proteins, Cricetinae, Mutation, Animals, Membrane Fusion, Endocytosis, Biotechnology, Cell Line, GTP Phosphohydrolases, rab5 GTP-Binding Proteins
selected citations These citations are derived from selected sources.This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).14 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Average influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Average impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Average
Citations provided by BIP!Popularity provided by BIP!