descriptionPublicationkeyboard_double_arrow_right Article 01 Sep 1985 English Publisher:Springer Science and Business Media LLCJournal:Cellular and Molecular Neurobiology, volume 5, pages 297-301 (issn: 0272-4340, eissn: 1573-6830,

Authors: Helmut L. Haas; Robert W. Greene;

doi: 10.1007/bf00711014

pmid: 2998625

pmc: PMC11572903

Long-term potentiation and 4-aminopyridine

- Summary
- Subjects
- Metrics

Abstract

Long-term potentiation (LTP) of excitatory postsynaptic potentials (epsp's) was investigated with extracellular field potential recording in hippocampal slices from rats. In the presence of 100 microM 4-aminopyridine (4-AP) the probability of eliciting LTP was unchanged or increased; the extent of potentiation was not significantly different from normal. During LTP saturation, 4-AP further enhanced the epsp. These data are inconsistent with an involvement of A-current reduction in LTP.

Related Organizations

University of Zurich
Switzerland

Keywords

Time Factors, Aminopyridines, Animals, Rats, Inbred Strains, 4-Aminopyridine, Evoked Potentials, Hippocampus, Electric Stimulation, Rats

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	11
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%