The ultrastructural morphology of the muscle fiber in myotonic dystrophy

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1968 English Publisher:Springer Science and Business Media LLCJournal:Acta Neuropathologica, volume 10, pages 218-241 (issn: 0001-6322, eissn: 1432-0533,

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Authors: J M, Schröder; R D, Adams;

doi: 10.1007/bf00687725

pmid: 4884471

The ultrastructural morphology of the muscle fiber in myotonic dystrophy

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Abstract

Biopsies from three patients with different clinical and pathological stages of myotonic dystrophy were studied by phase and electron microscopy. Large sarcoplasmic masses and spiral annulets were prominent in Cases 1 and 2 while in Case 3, featured clinically by atrophic weakness, they were infrequent. In the latter the residual fibers were either large and dystrophic or small and atrophic.

Related Organizations

Massachusetts General Hospital
United States
Harvard University
United States

Keywords

Adult, Cell Nucleus, Male, Cytoplasm, Cysts, Muscles, Middle Aged, Cytoplasmic Granules, Muscular Dystrophies, Mitochondria, Microscopy, Electron, Sarcolemma, Myofibrils, Humans, Female, Microscopy, Phase-Contrast

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