In two longitudinal studies, initial muscle strength and endurance of the shoulder-forearm muscles were related to deterioration of shoulder-neck-arm disorders after one year. Group I (n = 32) worked in the automobile industry assembling car motors. Their work was performed when standing and walking, and implied varied postures and exertion of external forces. Group II (n = 96) worked in the electronics industry assembling printed circuit boards. They worked sitting down and were exposed mainly to postural static loads. Muscle strength was negatively related to deterioration in group I but no such relationship was found in group II. The mechanism of occupational muscular injury is discussed, and it is suggested that mechanical overstress of the musculoskeletal system causes injury in occupations where external forces are exerted. The mechanism of injury in static, postural loads remains to be explained.