
doi: 10.1007/bf00635944
The ratio of 3- and 5-nitro isomers formed in the nitration of 2-pyridones with nitric acid is determined by the reaction temperature but is independent of the concentration of the nitrating agent. The presence of a phenyl group in the 6 position of the α-pyridone ring hinders incorporation of a nitro group in the 5 position.
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