
doi: 10.1007/bf00592854
pmid: 4588588
The origin of the genetic code is not merely an evolutionary juggling of codon assignments until some optimal configuration is achieved. It is, rather, the more interesting and profound problem of how codon assignments arose. This is part and parcel of the origin of a translating mechanism. A plausible scheme for the evolution of translation starting from a simple class of nucleic acid components is presented. Such an evolution may appear unique, idiosyncratic, when viewed only in terms of structural details. However, in its general features, on a more fundamental level, this evolution is a prototype study in the refinement of a process, in the emergence of macro-order. In approaching the evolution of the genetic code the biologist will be forced to reexamine many of his fundamental prejudices, indeed, the meaning of Biology itself.
Binding Sites, Base Sequence, Biological Evolution, Article, Models, Structural, Phenotype, Suppression, Genetic, Genes, RNA, Transfer, Genetic Code, RNA, Ribosomal, Protein Biosynthesis, Mutation, Nucleic Acid Conformation, Amino Acids, 500.sciences, Molecular Biology, Ribosomes, Protein Binding
Binding Sites, Base Sequence, Biological Evolution, Article, Models, Structural, Phenotype, Suppression, Genetic, Genes, RNA, Transfer, Genetic Code, RNA, Ribosomal, Protein Biosynthesis, Mutation, Nucleic Acid Conformation, Amino Acids, 500.sciences, Molecular Biology, Ribosomes, Protein Binding
| selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | 129 | |
| popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network. | Top 10% | |
| influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Top 1% | |
| impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network. | Top 10% |
