The evaluation of histamine antagonists in man
Copyright policy )The evaluation of histamine antagonists in man
A new method for evaluating histamine antagonists in man is described based on diminution of the effects of intradermal histamine. The inter and intra subject variability of such effects is examined experimentally and previous descriptions reviewed. Measures are adopted to minimise the effects and so achieve maximum economy of drug administrations and subjects. The method is exemplified by comparisons of activity of different preparations of triprolidine and of cyclizine and chlorcycline.
Male, Time Factors, Injections, Intradermal, Triprolidine, Administration, Oral, Injections, Intramuscular, Piperazines, Evaluation Studies as Topic, Histamine H1 Antagonists, Methods, Cyclizine, Humans, Histamine, Skin Tests
Male, Time Factors, Injections, Intradermal, Triprolidine, Administration, Oral, Injections, Intramuscular, Piperazines, Evaluation Studies as Topic, Histamine H1 Antagonists, Methods, Cyclizine, Humans, Histamine, Skin Tests
selected citations These citations are derived from selected sources.This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).38 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Average influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Top 1% impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Average
Citations provided by BIP!Popularity provided by BIP!