Exercise-induced asthma and doxantrazole

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1977 English Publisher:Springer Science and Business Media LLCJournal:European Journal of Clinical Pharmacology, volume 11, pages 107-109 (issn: 0031-6970, eissn: 1432-1041,

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Authors: H, Poppius; B, Stenius;

doi: 10.1007/bf00562900

pmid: 837962

Exercise-induced asthma and doxantrazole

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Abstract

In a double-blind cross-over trial in 13 patients with exercise-induced asthma, doxantrazole 200 mg taken orally 1 hour before a standardized exercise test involving stair climbing failed to block post-exercise bronchoconstriction. In an open assessment study with the same patients, increasing the doxantrazole dose to 400 mg did not affect post-exercise bronchoconstriction.

Related Organizations

Oulu University Hospital
Finland
Helsinki University Hospital
Finland

Keywords

Adult, Male, Time Factors, Adolescent, Physical Exertion, Histamine Antagonists, Tetrazoles, Peak Expiratory Flow Rate, Middle Aged, Asthma, Thioxanthenes, Humans, Female

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