Survival of BCG in rat tissues

descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 01 Jan 1971 English Publisher:Springer Science and Business Media LLCJournal:Internationales Archiv f�r Arbeitsmedizin, volume 28, pages 296-300 (issn: 0340-0131, eissn: 1432-1246,

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Authors: A, Swensson; C J, Göthe; B, Nyström;

doi: 10.1007/bf00539605

pmid: 4336038

Survival of BCG in rat tissues

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Abstract

Culture on Lowenstein medium shows that lungs, hilar lymph nodes and spleens from female albino rats injected intravenously with BCG, and then killed after observation periods up to 12 months, contain viable BCG. These organisms induced granulomatous tissue reactions in rat lungs, indicating that the resistance of rats to tubercle bacilli is only relative.

Related Organizations

Karolinska University Hospital
Sweden
National Institute of Occupational Health
Norway

Keywords

Time Factors, Virulence, Rats, Inbred Strains, Silicon Dioxide, Mycobacterium bovis, Rats, Animals, Female, Lymph Nodes, Lung, Spleen

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