Identification of harman in the rat arcuate nucleus

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1980 English Publisher:Springer Science and Business Media LLCJournal:NaunynSchmiedeberg's Archives of Pharmacology, volume 310, pages 227-230 (issn: 0028-1298, eissn: 1432-1912,

Copyright policy )

Authors: D W, Shoemaker; J T, Cummins; T G, Bidder; H G, Boettger; M, Evans;

doi: 10.1007/bf00499914

pmid: 7374793

Identification of harman in the rat arcuate nucleus

- Summary
- Subjects
- Metrics

Abstract

This communication describes the presence of 1-methyl-beta-carboline (harman) in the hypophysiotropic area of the hypothalamus which incorporates the arcuate nucleus. Diethyl ether extracts of borate-buffered arcuate homogenates were subjected to silica column chromatography and thin-layer chromatography (TLC). Identification of the beta-carboline was accomplished by use of fluorescent spectrometry, gas chromatography (GC), mass spectrometry (MS) and combined gas chromatography-mass spectrometry (GC-MS).

Related Organizations

Jet Propulsion Lab
United States
California Institute of Technology
United States
National Aeronautics and Space Administration
United States
University of California, Los Angeles
United States

Keywords

Male, Medulla Oblongata, Chromatography, Gas, Rats, Harmine, Alkaloids, Spectrometry, Fluorescence, Mesencephalon, Animals, Caudate Nucleus, Carbolines

Impact byBIP!

	selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	68
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%