On the similarity of tetanus and cholera toxins

descriptionPublicationkeyboard_double_arrow_right Article 01 Sep 1973 English Publisher:Springer Science and Business Media LLCJournal:Naunyn-Schmiedeberg's Archives of Pharmacology, volume 276, pages 280-295 (issn: 0028-1298, eissn: 1432-1912,

Copyright policy )

Authors: W E, van Heyningen;

doi: 10.1007/bf00499882

pmid: 4268160

On the similarity of tetanus and cholera toxins

- Summary
- Subjects
- Metrics

Abstract

There are several similarities between tetanus and cholera toxins, including their ability to react with ganglioside. However, tetanus toxin reacts mostly with certain gangliosides containing sialidase-sensitive bonds, whereas cholera toxin reacts only with one particular ganglioside that does not contain any sialidase-sensitive bonds. The possible implications of the similarities and dissimilarities of these two toxins are touched upon.

Related Organizations

University of Oxford
United Kingdom

Keywords

Binding Sites, Chemical Phenomena, Brain, Neuraminidase, Epithelium, Chemistry, Cholera, Tetanus Toxin, Gangliosides, Animals, Cattle, Neuraminic Acids, Chromatography, Thin Layer, Rabbits, Intestinal Mucosa, Toxins, Biological, Vibrio

Impact byBIP!

	selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	12
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%