Effect of tetanus toxin on the monosynaptic reflex

descriptionPublicationkeyboard_double_arrow_right Article 01 Jul 1983 English Publisher:Springer Science and Business Media LLCJournal:Naunyn-Schmiedeberg's Archives of Pharmacology, volume 323, pages 217-220 (issn: 0028-1298, eissn: 1432-1912,

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Authors: K, Takano; F, Kirchner; P, Terhaar; B, Tiebert;

doi: 10.1007/bf00497666

pmid: 6621716

Effect of tetanus toxin on the monosynaptic reflex

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Abstract

Tetanus toxin was injected at various doses (0.1-10,000 mouse MLD/kg) into the gastrocnemius muscle of the left hind leg of the cat. The relative excitability of the monosynaptic reflex (MSR) was increased in the very early period of the intoxication decreased in the later period, during which the MSR of the gastrocnemius was either partially or totally depressed at doses as low as 10 mouse MLD/kg.

Related Organizations

University of Göttingen
Germany

Keywords

Time Factors, Tetanus Toxin, Reflex, Monosynaptic, Movement, Cats, Animals, Electric Stimulation

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