Serum prealbumin in inbred strains of Mus musculus

descriptionPublicationkeyboard_double_arrow_right Article 01 Feb 1974 English Publisher:Springer Science and Business Media LLCJournal:Biochemical Genetics, volume 11, pages 97-102 (issn: 0006-2928, eissn: 1573-4927,

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Authors: L, Claxton; H V, Malling; H E, Walburg;

doi: 10.1007/bf00485767

pmid: 4824507

Serum prealbumin in inbred strains of Mus musculus

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Abstract

Separation of blood serum prealbumin from ten strains of inbred mice was accomplished using acrylamide electrophoresis. Nine of these strains demonstrated the same five prealbumin bands; however, the C57BL/6JWg strain showed a sixth band. The use of appropriate crosses of C57BL/6JWg and DBA/2fWg showed this unique band to be the product of a single autosomal dominant gene. We have named the gene for this prealbumin band Pre-1 and have shown a map distance between Pre-1 and b of 2.25 cM. Only one of the five prealbumins present in all strains of mice tested showed nonspecific esterase activity.

Related Organizations

National Institute of Environmental Health Sciences
United States
National Institutes of Health
United States
National Institute of Health
Pakistan
Research Triangle Park Foundation
United States

Keywords

Male, Chromosome Mapping, Mice, Inbred Strains, Blood Protein Electrophoresis, Mice, Phenotype, Animals, Hybridization, Genetic, Electrophoresis, Polyacrylamide Gel, Female, Protein Precursors, Crosses, Genetic, Serum Albumin, Genes, Dominant

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