Synthesis of carboline bases

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1969 English Publisher:Springer Science and Business Media LLCJournal:Chemistry of Heterocyclic Compounds, volume 3, pages 684-685 (issn: 0009-3122, eissn: 1573-8353,

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Authors: M. F. Petrova; N. S. Kaverina; G. P. Men'shikov;

doi: 10.1007/bf00468345

Synthesis of carboline bases

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Abstract

A study has been made of the condensation of serotonin with aldehydes to give the corresponding β-carboline derivatives. In most cases the reaction was run under biological conditions (pH 5. 4, 36‡). The following aldehydes were reacted: acetaldehyde, butyraldehyde, isobutyraldehyde, benzaldehyde, n-octaldehyde, and formaldehyde. The corresponding β-carboline derivatives are obtained from the first 5 of these. The reaction with formaldehyde leads to complete resinification.

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