Permeability of the round window membrane

descriptionPublicationkeyboard_double_arrow_right Article 01 Jun 1984 English Publisher:Springer Science and Business Media LLCJournal:Archives of oto-rhino-laryngology, volume 240, pages 103-106 (issn: 0302-9530,

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Authors: T, Okuno; Y, Nomura;

doi: 10.1007/bf00453466

pmid: 6591901

Permeability of the round window membrane

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Abstract

Cefmetazole sodium, a cephamycin antibiotic, was shown to pass through the round window membrane into the inner ear of the guinea pig. The concentration of the drug in the inner ear fluid indicated that a larger amount of the drug reached the inner ear through the round window membrane than when administered intraperitoneally.

Related Organizations

University of Tokyo
Japan

Keywords

Membranes, Round Window, Ear, Guinea Pigs, Animals, Cefmetazole, Cephamycins, Permeability, Cochlea

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