Photoallergic dermatitis from 8-methoxypsoralen
Copyright policy )Photoallergic dermatitis from 8-methoxypsoralen
A 36 year old woman with psoriasis vulgaris developed generalized photoallergic dermatitis to 8-methoxypsoralen after 16 uneventful treatments with 8-methoxypsoralen und UVA (PUVA). The diagnosis of photoallergy was confirmed by re-exposure to oral 8-methoxypsoralen and total body UVA irradiation; phototests using topical and oral 8-methoxypsoralen with a high intensity monochromator or with a new high intensity light apparatus for the delivery of UVA; and histological studies. Photoallergy occurred only with UVA, but not with UVB or UVC. There was no photoallergy following trimethylpsoralen.
Adult, Photochemotherapy, Ultraviolet Rays, Humans, Methoxsalen, Psoriasis, Female, Drug Eruptions, Photosensitivity Disorders
Adult, Photochemotherapy, Ultraviolet Rays, Humans, Methoxsalen, Psoriasis, Female, Drug Eruptions, Photosensitivity Disorders
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