Serotyping of fungal isolates by precipitating monoclonal antibodies
Copyright policy )Serotyping of fungal isolates by precipitating monoclonal antibodies
Ascites fluid from hybridoma cell lines producing monoclonal antibodies to an exoantigen of Microsporum canis was assayed for its precipitating properties. Three types of monoclonal antibodies were used for serological analysis of heterologous mycelial cultures. Based on specific antigenic determinants, the fungal strains showed different immunodiffusion reactivity within the species. The monoclonal antibodies also proved to be effective reagents for serotyping heterogeneous species. They may also have potential applications in epidemiology.
- Catholic University of the Sacred Heart Italy
- University of Parma Italy
- University of Milan Italy
Immunodiffusion, Mice, Inbred BALB C, Antigens, Fungal, animals ; antibodies, fungal ; antibodies, monoclonal ; antigens, fungal ; ascitic fluid ; epitopes ; immunodiffusion ; immunoglobulin G ; mice ; mice, inbred BALB C ; microsporum ; serotyping, Antibodies, Monoclonal, Epitopes, Mice, Immunoglobulin G, Animals, Ascitic Fluid, Microsporum, Serotyping, Antibodies, Fungal
Immunodiffusion, Mice, Inbred BALB C, Antigens, Fungal, animals ; antibodies, fungal ; antibodies, monoclonal ; antigens, fungal ; ascitic fluid ; epitopes ; immunodiffusion ; immunoglobulin G ; mice ; mice, inbred BALB C ; microsporum ; serotyping, Antibodies, Monoclonal, Epitopes, Mice, Immunoglobulin G, Animals, Ascitic Fluid, Microsporum, Serotyping, Antibodies, Fungal
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