Pathogenicity of the hyphae of Filobasidiella neoformans

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1983 English Publisher:Springer Science and Business Media LLCJournal:Mycopathologia, volume 81, pages 107-110 (issn: 0301-486X, eissn: 1573-0832,

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Authors: B L, Zimmer; H O, Hempel; N L, Goodman;

doi: 10.1007/bf00436987

pmid: 6343881

Pathogenicity of the hyphae of Filobasidiella neoformans

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Abstract

The pathogenicity of the purified hyphae of Filobasidiella neoformans was determined. The hyphal particles were inoculated into white Swiss female mice via the intracranial and intravenous route. Upon autopsy, infection was seen with as few as 25 hyphal elements. The brain, liver, and spleen were examined culturally and the brain examined histologically to prove the pathogenicity of the purified hyphae.

Related Organizations

University of Kentucky
United States

Keywords

Cryptococcus, Mice, Liver, Cryptococcus neoformans, Animals, Brain, Female, Spleen

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