
doi: 10.1007/bf00432291
pmid: 106429
The effects of lysergic acid diethylamide (LSD), d-amphetamine (AMP), chlorpromazine (CPZ), and the most active isomer of marihuana (delta9 - THC) on timing behavior were analyzed with a two-choice, discrete trial procedure in which pigeons were trained to discriminate visual stimuli that differed with respect to duration ('long' vs. 'short'). LSD (0.01, 0.04, 0.16 mg/kg) decreased response speed (increased latency), but otherwise had no significant effects on performance of the discrimination. d-Amphetamine (1.0, 2.0, 4.0 mg/kg) increased perseveration of 'spatial bias' and, at a dose of 4.0 mg/kg, lowered response speed. This compound did not significantly alter accuracy (percentage correct). CPZ (7.5, 15.0, 30.0 mg/kg) significantly decreased accuracy and, at a dose of 30.0 mg/kg, significantly lowered speed; THC also decreased accuracy and lowered speed. Neither CPZ nor THC significantly altered perseveration.
Male, Lysergic Acid Diethylamide, Dextroamphetamine, Discrimination, Psychological, Chlorpromazine, Time Perception, Animals, Dronabinol, Columbidae
Male, Lysergic Acid Diethylamide, Dextroamphetamine, Discrimination, Psychological, Chlorpromazine, Time Perception, Animals, Dronabinol, Columbidae
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