Central muscarinic receptors and male rat sexual behavior: Facilitation by oxotremorine but not arecoline or pilocarpine in methscopolamine pretreated animals
Copyright policy )Central muscarinic receptors and male rat sexual behavior: Facilitation by oxotremorine but not arecoline or pilocarpine in methscopolamine pretreated animals
Oxotremorine (0.1-0.8 mg/kg IP), but not arecoline (12-48 mg/kg IP), or pilocarpine (5-20 mg/kg IP), reduced both the number of intromissions to ejaculation and the ejaculation latency in methscopolamine-pretreated male rats. The effects of oxotremorine, (0.4 mg/kg IP) were completely antagonized by the administration of scopolamine (0.4 mg/kg IP). Methscopolamine (3-12 mg/kg IP), or scopolamine (0.2-0.4 mg/kg IP) did not by themselves produce any statistically significant effects on male rat sexual behavior.
- Astra Italy
- University of Gothenburg Sweden
Male, Dose-Response Relationship, Drug, Oxotremorine, Arecoline, Pilocarpine, Scopolamine Derivatives, Rats, Inbred Strains, N-Methylscopolamine, Receptors, Muscarinic, Rats, Sexual Behavior, Animal, Animals, Female
Male, Dose-Response Relationship, Drug, Oxotremorine, Arecoline, Pilocarpine, Scopolamine Derivatives, Rats, Inbred Strains, N-Methylscopolamine, Receptors, Muscarinic, Rats, Sexual Behavior, Animal, Animals, Female
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