Effect of caffeine on the memory of the mouse

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1979 English Publisher:Springer Science and Business Media LLCJournal:Psychopharmacology, volume 61, pages 29-30 (issn: 0033-3158, eissn: 1432-2072,

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Authors: J A, Izquierdo; S M, Costas; E A, Justel; G, Rabiller;

doi: 10.1007/bf00426806

pmid: 108716

Effect of caffeine on the memory of the mouse

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Abstract

Albino mice were injected i.p. with caffeine (27.9 mg/kg) 10 min pre-trial. The mice had no trial retention (300-s period) after 24 h. This result suggests that caffeine, at this dose, would upset some mechanism involved in memory processes. No correlation is observed between serotonin (5-HT) increase and caffeine's effect on retention.

Related Organizations

National Scientific and Technical Research Council
Argentina

Keywords

Male, Mice, Serotonin, Memory, Caffeine, Animals, Brain Stem

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