Biotransformation and toxicity of aniline and aniline derivatives in cyanobacteria

descriptionPublicationkeyboard_double_arrow_right Article 01 Dec 1981 English Publisher:Springer Science and Business Media LLCJournal:Archives of Microbiology, volume 130, pages 272-275 (issn: 0302-8933, eissn: 1432-072X,

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Authors: C E, Cerniglia; J P, Freeman; C, Van Baalen;

doi: 10.1007/bf00425939

pmid: 6800332

Biotransformation and toxicity of aniline and aniline derivatives in cyanobacteria

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Abstract

Agmenellum quadruplicatum strain PR-6 and Oscillatoria sp. strain JCM grown photoautotrophically in the presence of aniline metabolized the aromatic amine to formanilide, acetanilide and p-aminophenol. The metabolites were isolated by either thin-layer, gas-liquid or high pressure liquid chromatography and identified by comparison of their chromatographic, ultraviolet absorbance and mass spectral properties with those of authentic compounds. The toxicity of aniline derivatives towards Agmenellum quadruplicatum strain PR-6 indicated that the cyanobacterium was extremely sensitive to o-, m- and p-aminophenols, and phenylhydroxylamine.

Related Organizations

United States Food and Drug Administration
United States
Marine Science Institute
Philippines
National Center for Toxicological Research
United States

Keywords

Aniline Compounds, Cyanobacteria

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