Effects of infused tryptamine in man

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1970 English Publisher:Springer Science and Business Media LLCJournal:Psychopharmacologia, volume 18, pages 231-237 (issn: 0033-3158, eissn: 1432-2072,

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Authors: W R, Martin; J W, Sloan;

doi: 10.1007/bf00412669

pmid: 4922520

Effects of infused tryptamine in man

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Abstract

Tryptamine, infused intravenously in man, facilitates the patellar reflex, dilates pupils and elevates blood pressure. It also causes changes in vision and hearing, as well as nausea, vomiting, dizziness, sweating and heaviness of body. These changes are similar to those produced by LSD-like hallucinogens and are consistent with the hypothesis that LSD-like hallucinogens interact with tryptamine receptors as one mode of action.

Related Organizations

National Institutes of Health
United States
National Institute of Mental Health
United States
Addiction Research Center

Keywords

Clinical Trials as Topic, Epinephrine, Indoleacetic Acids, Dopamine, Receptors, Drug, Blood Pressure, Nausea, Pupil, Sweating, Hydrogen-Ion Concentration, Hydroxyindoleacetic Acid, Tryptamines, Lysergic Acid Diethylamide, Norepinephrine, Hearing, Creatinine, Reflex, Humans, Knee, Specific Gravity

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