
We have determined the base sequence of the restriction fragment Bam1-2 (3,593) of Paracentrotus lividus (sea urchin) mtDNA. This fragment contains, in addition to genes previously identified (part of the 12S rRNA, ND1 and part of the ND2 mRNA), a cluster of 15 tRNA genes located between the 12S and ND1 genes. Also to be found in the tRNA gene cluster, between the tRNA(Thr) and tRNA(Pro) genes, is a sequence of 134 bp which constitutes the only non-coding region of this DNA so far identified. The distinctive organization of the tRNA genes and the extreme size reduction of the non-coding region suggest the existence of unique mechanisms for the regulation of gene expression in this organism.
Base Sequence, Genes, RNA, Transfer, Sea Urchins, Molecular Sequence Data, Animals, Nucleic Acid Conformation, Amino Acid Sequence, DNA Restriction Enzymes, DNA, Mitochondrial
Base Sequence, Genes, RNA, Transfer, Sea Urchins, Molecular Sequence Data, Animals, Nucleic Acid Conformation, Amino Acid Sequence, DNA Restriction Enzymes, DNA, Mitochondrial
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