Production of recombinant proteins in serum-free media

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1991 English Publisher:Springer Science and Business Media LLCJournal:Cytotechnology, volume 5, pages 47-55 (issn: 0920-9069, eissn: 1573-0778,

Copyright policy )

Authors: D, Broad; R, Boraston; M, Rhodes;

doi: 10.1007/bf00365533

pmid: 1367051

Production of recombinant proteins in serum-free media

- Summary
- Subjects
- Metrics

Abstract

The advantages of serum-free culture for the manufacture of recombinant biopharmaceuticals from mammalian cells are reviewed. The process favoured is fed-batch serum-free cell culture. This process is applicable to the majority of cell lines, is practical on the large scale, gives the lowest manufacturing cost, and can be carried out without the use of any serum.

Keywords

Blood, Animals, Humans, Recombinant Proteins, Cell Line, Culture Media

Impact byBIP!

	selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	8
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Average