Hybridization of mRNA and pre-mRNA with the sequences forming double-stranded structures in pre-mRNA

descriptionPublicationkeyboard_double_arrow_right Article 01 Dec 1973 English Publisher:Springer Science and Business Media LLCJournal:Molecular Biology Reports, volume 1, pages 215-219 (issn: 0301-4851, eissn: 1573-4978,

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Authors: A P, Ryskov; S A, Limborska; G P, Georgiev;

doi: 10.1007/bf00357644

pmid: 24197569

Hybridization of mRNA and pre-mRNA with the sequences forming double-stranded structures in pre-mRNA

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Abstract

About 25% of the double-stranded sequences isolated from pre-mRNA are able to hybridize, after melting, with either mRNA or non-melted pre-mRNA. The retention of one branch of pre-mRNA hairpin in mRNA was suggested. It was also found that in addition to the hairpin-like structures comprising about 3% of the total sequences another 15% of the pre-mRNA sequences can form double-stranded structures upon annealing over a broad interval of Cot values.

Related Organizations

Russian Academy of Sciences
Russian Federation

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