Methylgroups of ribosomal protein L11 are not related to the synthesis of ppGpp

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1979 English Publisher:Springer Science and Business Media LLCJournal:Molecular and General Genetics MGG, volume 170, pages 187-189 (issn: 0026-8925, eissn: 1432-1874,

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Authors: R, Röhl; K H, Nierhaus;

doi: 10.1007/bf00337795

pmid: 372761

Methylgroups of ribosomal protein L11 are not related to the synthesis of ppGpp

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Abstract

Ribosomes carrying either a normally methylated or an undermethylated L11, respectively, were tested with respect to the stringency reaction in the presence of crude stringent factor. Systems with either kind of ribosomes synthesize ppGpp with the same efficiency. The ppGpp synthesis in presence of ribosomes with undermethylated L11 depends also on stringent factor, mRNA and deacylated tRNA whereas aminoacyl-tRNA and peptidyl-analogous tRNA show no effect. Thus, the absence of methylation in L11 does not influence the stringency reaction.

Related Organizations

Max Planck Society
Germany
Max Planck Institute for Molecular Genetics
Germany

Keywords

Ribosomal Proteins, Phenotype, Mutation, Escherichia coli, Guanosine Tetraphosphate, Methylation, Guanine Nucleotides

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