
doi: 10.1007/bf00332647
pmid: 5550312
In order to study P2 DNA synthesis by incorporation of tritium-labeled thymine, mitomycin C has been used to selectively suppress host DNA synthesis. Several conditional lethal mutants of P2 (temperature-sensitive as well as amber) have been tested for their ability to synthesize DNA under non-permissive conditions. Mutants representing the two “early” genes were found unable to synthesize DNA normally.
DNA, Viral, Mutation, Phosphorus Isotopes, Tritium, Coliphages, Mitomycins
DNA, Viral, Mutation, Phosphorus Isotopes, Tritium, Coliphages, Mitomycins
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