Cytoplasmic vesicles appear in conspicuous numbers during oogenesis in the fern Pteridium aquilinum. Two classes of vesicles are recognized: Golgi vesicles, of the order of 0.1 μ in diameter, and larger vesicles, of the order of 0.75 μ in diameter, apparently not derived from the Golgi apparatus. The larger vesicles are further divisible into those with mainly electron-transparent contents, and those with conspicuous amounts of electron-opaque material. Both kinds of larger vesicles are believed to be autophagic in nature, but may have different origins. Comparisons are made with the vesicles which arise during differentiation of female reproductive cells in other organisms, and the significance of the phenomenon is discussed.