Pharmacokinetics of intravenous diclofenac sodium in children

descriptionPublicationkeyboard_double_arrow_right Article 01 Mar 1990 English Publisher:Springer Science and Business Media LLCJournal:European Journal of Clinical Pharmacology, volume 38, pages 293-295 (issn: 0031-6970, eissn: 1432-1041,

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Authors: R, Korpela; K T, Olkkola;

doi: 10.1007/bf00315034

pmid: 2340849

Pharmacokinetics of intravenous diclofenac sodium in children

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Abstract

Diclofenac sodium 0.5 mg/kg i.v. was given preoperatively to small children (age 4-6 y). Vt and total plasma clearance were higher than in adults but the elimination half-life was similar.

Related Organizations

Helsinki University Hospital
Finland
University of Helsinki
Finland
Hospital District of Helsinki and Uusimaa
Finland
Helsinki Children's Hospital
Finland

Keywords

Diclofenac, Child, Preschool, Premedication, Humans, Anesthesia, Infusions, Intravenous, Half-Life

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