Neurogenic muscle hypertrophy
Copyright policy )Neurogenic muscle hypertrophy
Muscle hypertrophy is rare in denervating diseases. A patient with calf enlargement associated with L5-S1 radiculopathy and another with thenar, hypothenar, forearm and calf muscle hypertrophy in the course of chronic relapsing inflammatory demyelinating polyneuropathy are described. Gastrocnemius muscle biopsy revealed both type I and type II fibre hypertrophy in the former case and predominant type I fibre hypertrophy in the latter. Passive stretching and abnormal spontaneous muscular activity might have played a role in the origin of hypertrophy in both patients, but a satisfactory explanation for denervation hypertrophy has yet to be provided.
Male, Muscular Diseases, Biopsy, Muscles, Humans, Hypertrophy, Middle Aged
Male, Muscular Diseases, Biopsy, Muscles, Humans, Hypertrophy, Middle Aged
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